A sphenopalatine ganglion block is a commonly utilized treatment for atypical face pain, headaches, neuralgia, and additional painful conditions. The sphenopalatine ganglion is a nerve bundle that is located in the pterygopalatine fossa bone cavity directly under the nose and is a part of the parasympathetic, sympathetic, and sensory nervous systems. Patients who have not responded to typical medical management or those who have experienced side effects from typical medical management of their condition may also benefit from this treatment.